Causes pain or distress, e.g. a disease

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1. The first letter of the answer for Causes pain or distress, e.g. a disease puzzle is: A

A
 
 
 
 
 
 
 

2. The last letter of the answer for Causes pain or distress, e.g. a disease puzzle is: S

 
 
 
 
 
 
 
S

3. The answer to Causes pain or distress, e.g. a disease is:

A
F
F
L
I
C
T
S

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