Opioid developed as a morphine substitute

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1. The first letter of the answer for Opioid developed as a morphine substitute puzzle is: H

H
 
 
 
 
 

2. The last letter of the answer for Opioid developed as a morphine substitute puzzle is: N

 
 
 
 
 
N

3. The answer to Opioid developed as a morphine substitute is:

H
E
R
O
I
N

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