Annoys, makes someone cross

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1. The first letter of the answer for Annoys, makes someone cross puzzle is: I

I
 
 
 
 
 
 
 
 

2. The last letter of the answer for Annoys, makes someone cross puzzle is: S

 
 
 
 
 
 
 
 
S

3. The answer to Annoys, makes someone cross is:

I
R
R
I
T
A
T
E
S
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